Pentose Phosphate Pathway made simple. This pathway has two major jobs: Generate NADPH Produce ribose 5 phosphate NADPH protects cells from oxidative stress and supports fatty acid, cholesterol, steroid, nitric oxide, and respiratory burst Glutathione an overview ScienceDirect Topics NADPH homeostasis in cancer: functions, mechanisms and therapeutic implications Signal Transduction and Targeted Therapy Hexose Monophosphate Pathway or Pentose Phosphate Pathway Animations PharmaXChange.info