How GHK Peptide Works Signaling GHK acts as a switch for skin repair: Interacts with adenosine receptors reduces inflammation Activates MAPK ERK, PI3K Akt, TGF pathways Stimulates fibroblasts & keratinocytes boosts collagen, elastin The Effect of the Human Peptide GHK on Gene Expression Relevant to Nervous System Function and Cognitive Decline GHK Cu: The Peptide That Transforms Skin and Tissue Health Calibrate Hydration The Human Tripeptide GHKCu in Prevention of Oxidative Stress and Degenerative Conditions of Aging: Implications for Cognitive Health Pickart 2012 Oxidative Medicine and Cellular Longevity Wiley Online Library